Ormetoprim

Ormetoprim
Clinical data
Other names	Ormethoprim
Identifiers
	IUPAC name 5-[(4,5-Dimethoxy-2-methylphenyl)methyl]pyrimidine-2,4-diamine;
CAS Number	6981-18-6;
PubChem CID	23418;
ChemSpider	21899;
UNII	M3EFS94984;
KEGG	D05273;
ChEBI	CHEBI:94553;
ChEMBL	ChEMBL494760;
CompTox Dashboard (EPA)	DTXSID1046689 ;
ECHA InfoCard	100.027.497
Chemical and physical data
Formula	C14H18N4O2
Molar mass	274.324 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CC1=CC(=C(C=C1CC2=CN=C(N=C2N)N)OC)OC;
	InChI InChI=1S/C14H18N4O2/c1-8-4-11(19-2)12(20-3)6-9(8)5-10-7-17-14(16)18-13(10)15/h4,6-7H,5H2,1-3H3,(H4,15,16,17,18); Key:KEEYRKYKLYARHO-UHFFFAOYSA-N;

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Ormetoprim is an antibiotic used in veterinary medicine. Typically it is used in combination with sulfadimethoxine, and it is used in the poultry^[1] and aquaculture industries.^[2]

Ormetoprim, like other diaminopyrimidines such as trimethoprim, inhibits the reduction of dihydrofolic acid to tetrahydrofolic acid by bacterial cells.^[3]

References

^ Hofacre CL, Fricke JA, Inglis T (2013). "Antimicrobial Drug Use in Poultry". Antimicrobial Therapy in Veterinary Medicine. pp. 569–587. doi:10.1002/9781118675014.ch34. ISBN 978-0-470-96302-9.
^ Singh M, Singh P (2018). "Drugs and chemicals applied in aquaculture industry: A review of commercial availability, recommended dosage and mode of application" (PDF). Journal of Entomology and Zoology Studies. 6 (6): 903–907.
^ "PRIMOR - sulfadimethoxine and ormetoprim tablet". DailyMed. U.S. National Library of Medicine.

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[1] Hofacre CL, Fricke JA, Inglis T (2013). "Antimicrobial Drug Use in Poultry". Antimicrobial Therapy in Veterinary Medicine. pp. 569–587. doi:10.1002/9781118675014.ch34. ISBN 978-0-470-96302-9.

[2] Singh M, Singh P (2018). "Drugs and chemicals applied in aquaculture industry: A review of commercial availability, recommended dosage and mode of application" (PDF). Journal of Entomology and Zoology Studies. 6 (6): 903–907.

[3] "PRIMOR - sulfadimethoxine and ormetoprim tablet". DailyMed. U.S. National Library of Medicine.

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