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Sulfafurazole

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Not to be confused with sulfadiazine.
Sulfafurazole
Clinical data
AHFS/Drugs.comInternational Drug Names
MedlinePlusa601049
Pregnancy
category
  • To be avoided within two months of term
Routes of
administration		Oral
ATC code
Legal status
Legal status
  • In general: ℞ (Prescription only)
Pharmacokinetic data
ExcretionExcreted unchanged in urine
Identifiers
  • 4-Amino-N-(3,4-dimethyl-1,2-oxazol-5-yl)benzenesulfonamide
CAS Number
PubChem CID
DrugBank
ChemSpider
UNII
KEGG
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.004.418 Edit this at Wikidata
Chemical and physical data
FormulaC11H13N3O3S
Molar mass267.30 g·mol−1
3D model (JSmol)
Melting point194 °C (381 °F)
  • CC1=C(ON=C1C)NS(=O)(=O)C2=CC=C(C=C2)N
  • InChI=1S/C11H13N3O3S/c1-7-8(2)13-17-11(7)14-18(15,16)10-5-3-9(12)4-6-10/h3-6,14H,12H2,1-2H3
  • Key:NHUHCSRWZMLRLA-UHFFFAOYSA-N
 ☒NcheckY (what is this?)  (verify)

Sulfafurazole (INN, also known as sulfisoxazole) is a sulfonamide antibacterial with an dimethyl-isoxazole substituent. It possesses antibiotic activity against a wide range of Gram-negative and Gram-positive organisms.[1] It is sometimes given in combination with erythromycin (see erythromycin/Sulfafurazole) or phenazopyridine. It is used locally in a 4% solution or ointment.

References

  1. ^ Holmes NE, Grauson ML (October 2017). "Sulfonamides". In Paterson DL, McCarthy JS, Mouton JW, Mills J, Grayson ML, Cosgrove SE, Crowe S, Hope W (eds.). Kucers' The Use of Antibiotics (7th ed.). CRC Press. pp. 1571–1624. ISBN 978-1-4987-4796-7.


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