Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Clinical Trial
. 2000 Sep;74(3):498-503.
doi: 10.1016/s0015-0282(00)00687-7.

Randomized trial of a "stage-of-change" oriented smoking cessation intervention in infertile and pregnant women

E G Hughes  1 , D A Lamont, M L Beecroft, D M Wilson, B G Brennan, S C Rice
Affiliations
Free article
Clinical Trial

Randomized trial of a "stage-of-change" oriented smoking cessation intervention in infertile and pregnant women

E G Hughes et al. Fertil Steril. 2000 Sep.
Free article

Abstract

Objective: To assess a "stage-of-change" oriented smoking cessation intervention for infertile and pregnant women, compared with standard of care.

Design: Randomized controlled trial.

Setting: Three university teaching hospitals in Hamilton, Ontario, Canada.

Patient(s): Infertile women at their first visit to a tertiary referral infertility clinic (n = 94) and new patients seeking pre-natal care (n = 110) who had smoked >/= 3 cigarettes in the past six months.

Intervention(s): A three to five minute scripted intervention and booklet specific to the woman's "stage-of-change" in the smoking continuum, versus standard of care. Exhaled carbon-monoxide (CO) monitoring was used to validate exposure in both groups.

Main outcome measure(s): Delta "stage-of-change" and rate of maintained cessation at 12 months post follow-up.

Result(s): Intervention and control were similarly effective for infertile women: the rate of maintained cessation rose significantly from 4% to 24% over twelve months, with a mean delta "stage-of-change" 0.28. In prenatal women, neither approach was effective. Maintained cessation did not significantly change from 0 to 12 months (19% to 18%). Mean delta "stage-of-change" declined by -0.62.

Conclusion(s): For infertile women, basic information describing the impact of smoking on fertility, along with exhaled CO monitoring and a more intensive intervention were both highly effective. In pregnant women neither approach was beneficial, with some evidence of post-partum relapse.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

Publication types

Substances

LinkOut - more resources