Today is an exciting day of firsts for Strand Therapeutics. We are proud to announce the dosing of our first patient with STX-001 in our first Phase 1 trial for the treatment of cancer patients with solid tumors. STX-001 represents the first-ever programmable mRNA therapy to enter clinical trials. STX-001 is an investigational multi-mechanistic, synthetic self-replicating mRNA technology that expresses an IL-12 cytokine for an extended duration, directly into the tumor microenvironment. Join us at ASCO for more information on the trial design: Presentation Date/Time: 6/1/2024 9:00AM-12:00PM CDT Title: A phase I trial of intratumoral STX-001: A novel self-replicating mRNA expressing IL-12 alone or with pembrolizumab in advanced solid tumors. Session: Developmental Therapeutics -- Immunotherapy Location: McCormick Place, Chicago, Illinois, Hall A Poster Board Number: 161b Permanent Abstract Number: TPS2696 Read our press release: https://lnkd.in/g-j9vq6v #Programmable #mRNA #Oncology #ClinicalTrials #FirstPatientDosed #ASCO24 #ASCO2024
Strand Therapeutics
Biotechnology Research
Boston, Massachusetts 17,665 followers
Where synthetic biology meets RNA therapeutics
About us
Strand was founded by biological engineers working together at the Massachusetts Institute of Technology (MIT). Building on the idea of creating smart therapies capable of making sophisticated decisions, they sought to apply this concept to the emerging field of mRNA therapeutics. This area was previously untapped by traditional synthetic biology, leading us to build our very own mRNA programming language, creating the world’s first platform for mRNA smart therapies. Strand’s mRNA programming technology promises to make mRNA therapies safer and more effective by programming the location, timing, and intensity of therapeutic protein expression inside a patient’s body via mRNA-encoded logic circuits. These circuits have the ability to implement cell-type specific expressions by sensing and classifying the unique mRNA expression signatures of cells and control the dosage of protein expression through responses to exogenously administered small molecules.
- Website
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https://www.strandtx.com
External link for Strand Therapeutics
- Industry
- Biotechnology Research
- Company size
- 51-200 employees
- Headquarters
- Boston, Massachusetts
- Type
- Privately Held
- Founded
- 2017
- Specialties
- biotechnology, synthetic biology, RNA therapeutics, and Immunotherapy
Locations
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Primary
21-27 Burlington Ave
Boston, Massachusetts 02215, US
Employees at Strand Therapeutics
Updates
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Thrilled to share that Ashlesha Odak, PhD will be presenting breakthrough research at #ASGCT2024! Join us on Friday, 5/10/2024, in the Exhibit Hall to explore the potential of circular RNA-based CAR-T cell therapy for combating cancer. Session Details: Presentation Date/Time: 5/10/2024, Noon - 1:30 PM & 5:30 - 7 PM Title: Circular RNA Based Chimeric Antigen Receptor (CAR) Cell Therapy for Potent and Long-lasting Anti-Tumor Activity Session: Friday Posters: In Vivo Therapy Approaches Presentation Room: Exhibit Hall Abstract #: 1825 This groundbreaking in-body engineering approach promises to revolutionize the landscape of cell therapy, eliminating the traditional complexities associated with ex vivo therapies. By significantly slashing treatment costs and expanding access, this innovative method is set to transform medical care, bringing crucial therapies within reach of more patients. Don’t miss out on how we are advancing the frontiers of cancer treatment with our latest research. #ASGCT24 #CARTherapy #CancerTherapy #InVivoTherapy #BiotechInnovation #Biotech
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Excited to announce that Wen Allen Tseng will be presenting our groundbreaking research at #ASGCT2024! Join us on 5/9/2024 in the Exhibit Hall for an in-depth look at STX-003, our latest innovation in programmable mRNA cancer therapy. Session Details: Presentation Date/Time: 5/9/2024, Noon - 1:30 PM & 5:30 - 7 PM Title: STX-003: A Novel Systemically-Delivered mRNA-Based Cancer Therapy Utilizing a Programmable Genetic Circuit Platform for Tumor-Specific Protein Expression and Reduced Toxicity Session: Thursday Posters: Cancer - Immunotherapy and Cancer Vaccines Presentation Room: Exhibit Hall Abstract #: 1272 STX-003 is designed to revolutionize cancer treatment through a programmable genetic circuit platform, enabling tumor-specific protein expression with significantly reduced toxicity. Don’t miss out on how we’re pushing the boundaries of science to fight cancer more effectively. #ASGCT24 #mRNA #CancerTherapy #Immunotherapy #CancerVaccine #BiotechInnovation #Biotech
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We are thrilled to announce that we’ve been selected as a spoke of the ARPA-H Investor Catalyst Hub network! 🎉 We are excited to be a part of this nationwide network dedicated to accelerating groundbreaking advances in science and medicine—all in pursuit of better health outcomes for everyone. #ARPAH #ARPANETH #MedTech #HealthTech #InvestorCatalystHub #HealthInnovation
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Strand Therapeutics reposted this
Find out how scientists at Strand Therapeutics are using Benchling to shorten process development cycles — and build curative mRNA therapeutics — by harnessing data at scale. “As a PD scientist, if we have a more holistic view of our historical data, we can create more efficient plans for optimization strategies,” says Mae Kingsbury. https://lnkd.in/eyQHz6Pe #BuiltOnBenchling
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This weekend, a few Strands volunteered as judges at the MSEF High School Science Fair! Here's a pic from the fair at Gillette Stadium 🔬⚗ #BioTechNews #BioTech #mRNAResearch #mRNA #mRNATherapies
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Last week, Secretary Yvonne Hao and Jeanne LeClair, of the Massachusetts Life Science Center (MLSC), came by for a tour of the Strand office and labs! We're so excited about our ongoing work with MLSC. Here's a picture from their visit! #BioTechNews #BioTech #mRNAResearch #mRNA #mRNATherapies
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Strand spun out of MIT officially 5 years ago this month! To celebrate, MIT News spoke with our cofounder and CEO, Jacob Becraft, about the spin out process and the vision for the company’s MIT-originated technology! Read it here: https://lnkd.in/g6QgRAUN Massachusetts Institute of Technology #BioTechNews #BioTech #mRNAResearch #mRNA #mRNATherapies
Unlocking mRNA’s cancer-fighting potential
news.mit.edu
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Last week, Strand had the honor of hosting a group of biotech student entrepreneurs from top universities in Japan. We're committed to our connections and partnerships across the world! Here are some pictures from their visit. #BioTechNews #BioTech #mRNAResearch #mRNA #mRNATherapies The University of Tokyo
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We're celebrating #InternationalWomensDay2024 here at Strand! Imagine a gender equal world, free of bias, stereotypes, and discrimination. A world that's diverse, equitable, and inclusive, where difference is valued and celebrated. Collectively we can all #InspireInclusion. #InternationalWomensDay2024 #BioTechNews #BioTech #mRNAResearch #mRNA #mRNATherapies
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