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. 2016 Jan-Mar;14(1):708.
doi: 10.18549/PharmPract.2016.01.708. Epub 2016 Mar 15.

Women's involvement in clinical trials: historical perspective and future implications

Katherine A Liu  1 , Natalie A Dipietro Mager  2
Affiliations

Women's involvement in clinical trials: historical perspective and future implications

Katherine A Liu et al. Pharm Pract (Granada). 2016 Jan-Mar.

Abstract

The importance of considering the differences between the male and female sex in clinical decision-making is crucial. However, it has been acknowledged in recent decades that clinical trials have not always adequately enrolled women or analyzed sex-specific differences in the data. As these deficiencies have hindered the progress of understanding women's response to medications, agencies in the United States have worked towards the inclusion of women in clinical trials and appropriate analysis of sex-specific data from clinical trials. This review outlines the history and progress of women's inclusion in clinical trials for prescription drugs and presents considerations for researchers, clinicians, and academicians on this issue.

Keywords: Clinical Trials as Topic; Female; Patient Participation; Research; United States; Women’s Health.

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Conflict of interest statement

CONFLICT OF INTEREST

The authors have no conflict of interest with this article. No funding was provided.

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