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Review
. 2018 Sep 1:26:S19-S22.
doi: 10.1016/j.nmni.2018.08.016. eCollection 2018 Nov.

Mansonellosis, the most neglected human filariasis

O Mediannikov  1 , S Ranque  2
Affiliations
Review

Mansonellosis, the most neglected human filariasis

O Mediannikov et al. New Microbes New Infect. .

Abstract

Human mansonellosis is caused by M. perstans, M. ozzardi and M. streptocerca, the three main filarial species in the genus Mansonella. Despite accumulating evidence of a high prevalence in endemic areas, there is currently no filariasis control programme targeting mansonellosis. The health-related impact on people living with these filariae remains unknown, and evidences regarding treatment strategies are scarce. Like other neglected diseases, it mainly affects poor populations living in tropical and subtropical climates. Mansonellosis can be considered one of the most neglected tropical infectious diseases. The objective of this literature review was to draw attention to the gap of knowledge regarding Mansonella spp. taxonomy, the transmission of these arthropod-borne filariasis and the health outcomes of people living with mansonellosis.

Keywords: Filariasis; Mansonella ozzardii; Mansonella perstans; Mansonella streptocerca; neglected tropical diseases.

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Figures

Fig. 1
Fig. 1
Mansonella perstans microfilaria in thick blood film collected from a Senegalese patient (Giemsa straining; original magnification, ×1000).
Fig. 2
Fig. 2
Village in Oriental Senegal in which half of inhabitants are living with mansonellosis.
See this image and copyright information in PMC

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