Schizophrenia and Schizoaffective Disorders
Schizophrenia and schizoaffective disorders are severe mental conditions characterized by hallucinations, delusions, and mood disturbances. The Journal of Clinical Psychiatry offers a deep dive into these disorders, emphasizing their diagnosis, management, and underlying causes. Our expert editors ensure content is both clinically relevant and actionable, aiding psychiatrists in offering effective and compassionate care.
NEWS
New research provides insights into cognitive challenges, including age-related decline and the effects of psychiatric medications.
NEWS
This week explores the link between BP and EDs, managing treatment-resistant schizophrenia, and a new FDA-approved Alzheimer's drug.
ROUNDS IN THE GENERAL HOSPITAL
If you have ever been uncertain about how to evaluate patients with a chronic psychotic illness or struggled over how best to manage treatment-resistant schizophrenia, then this case vignette and discussion should prove useful.
Prim Care Companion CNS Disord. 2024;26(4):23f03692.
Carol S. Lim and others
NEWS
Emerging research has convinced modern psychiatry to reconsider catatonia as a symptom of schizophrenia rather than a standalone condition.
NEWS
A growing contingent has called for fewer clozapine restrictions, while concerns about side effects and treatment disparities persist.
NEWS
This week we report on a bevy of clozapine research, a promising Esmethadone case study, and let our readers take it from there.
CLINICAL AND PRACTICAL PSYCHOPHARMACOLOGY
Dr Andrade discusses two studies that examined the outcomes of gradual, individualized antipsychotic dose reduction and discontinuation in patients with psychosis.
J Clin Psychiatry. 2024;85(2):24f15363
Chittaranjan Andrade
ORIGINAL RESEARCH
Clozapine exposure of at least 5 years was associated with hematologic malignancy, and the increased risk was dose-dependent.
J Clin Psychiatry. 2024;85(2):23m15149
Delaney R. Brainerd and others
ORIGINAL RESEARCH
Clozapine plus LAI antipsychotics was associated with lower risk of rehospitalization compared to both clozapine plus oral antipsychotics and clozapine monotherapy.
J Clin Psychiatry 2024;85(2):23m15071
Yun Tien and others
ORIGINAL RESEARCH
Clozapine initiation is uncommon in people with psychotic disorders who have experienced events suggesting clozapine is indicated, with even lower rates in Black and Hispanic patients.
J Clin Psychiatry 2024;85(2):23m14833
Gregory E. Simon and others