Febarbamate (INN; Solium, Tymium), also known as phenobamate, is an anxiolytic and tranquilizer of the barbiturate and carbamate families which is used in Europe by itself and as part of a combination drug formulation called tetrabamate.[1][2][3][4]

Febarbamate
Clinical data
Other namesMS-543
ATC code
Identifiers
  • [1-butoxy-3-(5-ethyl-2,4,6-trioxo-5-phenyl-1,3-
    diazinan-1-yl)propan-2-yl] carbamate
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.032.919 Edit this at Wikidata
Chemical and physical data
FormulaC20H27N3O6
Molar mass405.451 g·mol−1
3D model (JSmol)
  • C1(=O)NC(C(C(=O)N1CC(OC(=O)N)COCCCC)(C2=CC=CC=C2)CC)=O
  • InChI=1S/C20H27N3O6/c1-3-5-11-28-13-15(29-18(21)26)12-23-17(25)20(4-2,16(24)22-19(23)27)14-9-7-6-8-10-14/h6-10,15H,3-5,11-13H2,1-2H3,(H2,21,26)(H,22,24,27) checkY
  • Key:QHZQILHUJDRDAI-UHFFFAOYSA-N checkY
 ☒NcheckY (what is this?)  (verify)

See also

edit

References

edit
  1. ^ World Health Organization (2004). "The use of stems in the selection of International Nonproprietary Names (INN) for pharmaceutical substance" (PDF).
  2. ^ Index nominum 2000: international drug directory. Taylor & Francis US. 2000. p. 427. ISBN 978-3-88763-075-1. Retrieved 26 November 2011.
  3. ^ Gentili E (March 1972). "[Therapeutic effects of a new psycholeptic agent (febarbamate, Solium) in pediatrics]". Minerva Medica (in Italian). 63 (18): 1058–60. PMID 5016064.
  4. ^ Morton I, Hall JM (1999). Concise dictionary of pharmacological agents: properties and synonyms. Springer. p. 118. ISBN 978-0-7514-0499-9. Retrieved 26 November 2011.