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ABCF1

From Wikipedia, the free encyclopedia
ABCF1
Identifiers
AliasesABCF1, ABC27, ABC50, ATP binding cassette subfamily F member 1
External IDsOMIM: 603429; MGI: 1351658; HomoloGene: 849; GeneCards: ABCF1; OMA:ABCF1 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001090
NM_001025091

NM_013854

RefSeq (protein)

NP_001020262
NP_001081

NP_038882

Location (UCSC)Chr 6: 30.57 – 30.6 MbChr 17: 36.27 – 36.28 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

ATP-binding cassette sub-family F member 1 is a protein that in humans is encoded by the ABCF1 gene.[5][6]

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the GCN20 subfamily. Unlike other members of the superfamily, this protein lacks the transmembrane domains, characteristic of most ABC transporters. This protein may be regulated by tumor necrosis factor-alpha and play a role in enhancing protein synthesis and inflammation.[6]

See also

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References

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  1. ^ a b c ENSG00000225989, ENSG00000236149, ENSG00000232169, ENSG00000204574, ENSG00000236342, ENSG00000231129 GRCh38: Ensembl release 89: ENSG00000206490, ENSG00000225989, ENSG00000236149, ENSG00000232169, ENSG00000204574, ENSG00000236342, ENSG00000231129Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000038762Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Richard M, Drouin R, Beaulieu AD (Dec 1998). "ABC50, a novel human ATP-binding cassette protein found in tumor necrosis factor-alpha-stimulated synoviocytes". Genomics. 53 (2): 137–45. doi:10.1006/geno.1998.5480. PMID 9790762.
  6. ^ a b "Entrez Gene: ABCF1 ATP-binding cassette, sub-family F (GCN20), member 1".

Further reading

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This article incorporates text from the United States National Library of Medicine, which is in the public domain.