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MTX1

From Wikipedia, the free encyclopedia
MTX1
Identifiers
AliasesMTX1, MTX, MTXN, metaxin 1
External IDsOMIM: 600605; MGI: 103025; HomoloGene: 37623; GeneCards: MTX1; OMA:MTX1 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_002455
NM_198883

NM_001161824
NM_013604
NM_001357367

RefSeq (protein)

NP_002446
NP_942584

n/a

Location (UCSC)Chr 1: 155.21 – 155.21 MbChr 3: 89.12 – 89.13 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Metaxin 1, also known as MTX1, is a protein which in humans is encoded by the MTX1 gene.[5][6]

Function

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The metaxin gene, which encodes a protein located on the outer membrane of mitochondria, is a component of the mitochondrial protein translocation apparatus.[7]

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000173171Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000064068Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: MTX1 metaxin 1".
  6. ^ Bornstein P, McKinney CE, LaMarca ME, Winfield S, Shingu T, Devarayalu S, Vos HL, Ginns EI (May 1995). "Metaxin, a gene contiguous to both thrombospondin 3 and glucocerebrosidase, is required for embryonic development in the mouse: implications for Gaucher disease". Proc. Natl. Acad. Sci. U.S.A. 92 (10): 4547–51. Bibcode:1995PNAS...92.4547B. doi:10.1073/pnas.92.10.4547. PMC 41981. PMID 7753840.
  7. ^ Armstrong LC, Komiya T, Bergman BE, Mihara K, Bornstein P (March 1997). "Metaxin is a component of a preprotein import complex in the outer membrane of the mammalian mitochondrion". J. Biol. Chem. 272 (10): 6510–8. doi:10.1074/jbc.272.10.6510. PMID 9045676.[permanent dead link]

Further reading

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