Sanford Burnham Prebys

Sanford Burnham Prebys

Research Services

La Jolla, CA 14,665 followers

We conduct world-class, collaborative, biological research and translate discoveries for the benefit of patients.

About us

Sanford Burnham Prebys is a preeminent, independent biomedical research institute dedicated to understanding basic human biology and disease and advancing scientific discoveries to profoundly impact human health. Our track record of pioneering research spans more than 40 years and has produced breakthroughs in cancer, neuroscience, immunology and children’s diseases and is anchored by our NCI-designated Cancer Center. Sanford Burnham Prebys’ drug discovery center and global partnerships propel our prototype drugs and therapeutic strategies toward improving human health. A deep culture of collaboration and commitment to educating the next generation of scientists unites Sanford Burnham Prebys researchers, partners and philanthropists in a shared mission to improve human health.

Website
http://www.sbpdiscovery.org
Industry
Research Services
Company size
501-1,000 employees
Headquarters
La Jolla, CA
Type
Nonprofit
Founded
1976
Specialties
stem cells, drug discovery, cancer research, diabetes research, rare and neglected diseases, neurodegenerative diseases, metabolism and obesity, children's diseases, core technology services, infectious and inflammatory diseases, aging research, pediatric cancer research, Crohn's disease, autism, inflammatory bowel disease, brain injuries, Alzheimer's disease, Parkinson's disease, cardiovascular disease, and calcification

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Employees at Sanford Burnham Prebys

Updates

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    Step into the complex world where addiction meets cancer. According to the 2022 National Survey on Drug Use and Health (NSDUH), 48.7 million Americans had substance use disorder (SUD) last year.   Join our upcoming open house hosted by the Community Advisory Board and the NCI-Designated Cancer Center at Sanford Burnham Prebys to learn about how SUD increases the risk of cancer. Meet dedicated scientists and clinicians, tour the labs, and get answers to your most pressing questions. Free and open to the public. Register now: https://bit.ly/3RzJk2T For more on NSDUH, visit: https://bit.ly/2022NSDUH  #cancer #cancercenter #cancerresearch #addiction #addictionresearch #NCI #NIH #NIDA #NSDUH #SAMHSA #sandiego #lajolla #torreypines 

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    The San Diego Nathan Shock Center is accepting applications for its Pilot Grant program. Scientists interested in studying the biology of aging can receive up to $20,000 ($50,000 for spatial-omics or longitudinal single-cell studies) for services, supplies, training workshops and travel to San Diego. Applications are due August 22, 2024. For more information on eligibility, application requirements and to apply, visit https://bit.ly/3B5VVjU #grantopportunity #researchfunding #sciencefunding #grants Salk Institute for Biological Studies, UC San Diego

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    Congratulations to Aryaman Bhattacharya who won The Lee Summer Student Fellowship! Recently graduated from the BS/MS contiguous program in Biology at UCSD, Aryaman will now transition to his master’s in Debanjan Dhar’s lab at Sanford Burnham Prebys. Aryaman will study if inhibiting Ubiquitin D confers protective effects against alcoholic liver disease, which could pave the way for new therapeutic approaches to treat ALD and related liver disorders—including cancer. The Fellowship is given by the Southern California Center of ALPD and Cirrhosis within the Keck School of Medicine of USC. More: https://lnkd.in/gfXYpUbD

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    David Brenner’s latest essay for The San Diego Union-Tribune’s Community Voices Project is now live. “𝐎𝐩𝐢𝐧𝐢𝐨𝐧: 𝐓𝐡𝐞𝐫𝐞’𝐬 𝐚 𝐬𝐞𝐜𝐫𝐞𝐭 𝐭𝐨 𝐥𝐢𝐯𝐢𝐧𝐠 𝐥𝐨𝐧𝐠 𝐚𝐧𝐝 𝐡𝐞𝐚𝐥𝐭𝐡𝐲," describes how living a vigorous life: walking, gardening and enjoying sex well into the golden years, can lead to a longer well-lived life. Read the full article here: https://bit.ly/3VCsi5D.

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    Sanford Burnham Prebys recognized the beginning of Pride month with a Pride flag-raising event on Friday, June 7, 2024. The gathering included an opportunity for speakers in a variety of roles throughout the Institute to share comments on the meaning of the Pride flag in their lives and careers. 🏳️🌈 David Brenner, M.D., president, CEO and Donald Bren Chief Executive Chair at Sanford Burnham Prebys, opened the ceremony, saying, “I’m very proud of everyone for working together to make this a welcoming community.” Alessandra (Lale) Cecchini, Ph.D., postdoctoral associate in the lab of Alessandra Sacco, Ph.D., concluded the formal ceremony, reflecting, “This gesture speaks loudly about who we are and what we stand for in terms of valuing acceptance, unity, respect and kindness.” She added, “While we have come a long way, we still have further to go. I hope this and other diversity-related events on campus encourage you to feel safe and empowered to fully be yourself.” Learn more about the event: https://bit.ly/4bU4UXX #pride #pridemonth #dei #deib #diversity #equity #inclusion #belonging

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    🎓❤️ On Friday, May 31, 2024, the Sanford Burnham Prebys Graduate School of Biomedical Sciences hosted four graduates, their family members and friends as well as current students, faculty members and staff at the Institute’s campus in La Jolla for the school’s first-ever Commencement ceremony. In addition to honoring the four graduates in attendance, the event also recognized the 62 other alumni who graduated from the Institute’s graduate school in the nearly 20 years since its founding in 2006. “The faculty and community at Sanford Burnham Prebys have been tremendous and afforded me the most meaningful opportunities to learn and grow,” said Stephen Sakuma, Ph.D. ’24, during his speech on behalf of Sanford Burnham Prebys alumni. “The journey has been long and, at times, arduous, but it also has been exceedingly rewarding.” Read more: https://bit.ly/3yWww0f #graduateschool #scientificresearch 📸 Pictured from left to right are Rachael McVicar, Ph.D. ’23; James Kent, Ph.D. ’22; Monica Gonzalez Ramirez, Ph.D. ’18; and Stephen Sakuma, Ph.D. ’24.

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    Congratulations to Chiara Nicoletti, Ph.D., one of three winners of the Young Investigators Award at the 2024 Dysferlin Conference organized by Jain Foundation Inc. Nicoletti, a member of the Puri laboratory at Sanford Burnham Prebys, played a crucial role in analyzing and characterizing single-cell and single-nucleus gene expression in dysferlin-deficient muscle, a challenging task given the wide breadth of data. Nicoletti's efforts have led to a deepened understanding of #dysferlinopathy, a group of inherited muscle diseases characterized by progressive muscle weakness and atrophy. The conditions, for which there are no treatments or cures, are caused by a mutation in the gene that makes #dysferlin, which is important for efficient muscle repair.

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    We congratulate the winners of the Young Investigators Awards from the 2024 Dysferlin Conference.   Alastair Khodabukus, Ph.D.,laboratory of Prof. Nenad Bursac, Duke University—Ali was instrumental in developing techniques for growing functional myobundles from iPS cells, and for characterizing and investigating several phenotypic abnormalities in dysferlin-deficient myobundles, involving calcium handling, cholesterol homeostasis, and metabolism. His work has yielded new insights into the function of dysferlin and identified potential treatment approaches.   Stacey Nicole Keenan, Ph.D., laboratory of Prof. Matthew Watt, University of Melbourne—Stacey’s work has led to the identification and characterization of the extensive changes in lipid composition, storage, metabolism, and regulation that occur in muscle as a result of dysferlin deficiency. This work has shown the lipid abnormalities to be a distinctive key feature of dysferlinopathy, rather than a nonspecific downstream effect, raising potential therapeutic targets.   Chiara Nicoletti, Ph.D., laboratory of Prof. Lorenzo Puri, Sanford Burnham Prebys Medical Discovery Institute—Chiara has played a leading role in data analysis in an ambitious undertaking involving three research groups to characterize single cell- and single nucleus gene expression in dysferlin deficient muscle. It has been known that in dysferlin deficiency there are large numbers of inflammatory infiltrates, but characterizing the cells, what genes they are expressing, and how they interact with each other is challenging. Chiara’s work in analyzing this large data set has been instrumental in increasing our understanding.

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    Brooke M. Emerling, Ph.D., is contributing to a revival of interest in an underappreciated set of enzymes called phosphatidylinositol-5-phosphate 4-kinases (PI5P4Ks). Emerling and team have now shown for the first time that PI5P4K activity is connected to the regulation of an ancient signaling system called the hippo pathway, which is found in a wide variety of organisms and is known to help human organs grow and control their size. In a study published in Science Signaling, Emerling and co-senior author Raymond Blind, Ph.D., at Vanderbilt University Medical Center, shared their findings, which open new research avenues to tackle aggressive cancers. Read more: https://bit.ly/3Vhg3wh #enzymes #PI5P4K #cancerresearch

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