Vectron Biosolutions AS

🌟 Protein Secretion in E. coli - Exciting Breakthrough at Vectron Biosolutions! 🌟 We are thrilled to announce that our latest secretion studies have yielded fantastic results, showcasing the transformative potential of our innovative technology. We've successfully achieved high secretion levels of multiple, industrially valuable proteins, marking a significant milestone in our journey to revolutionize protein manufacturing. 🧬 Proteins Successfully Expressed & Secreted Include: ·      GLP-1 ·      Insulin ·      Glucagon ·      Calcitonin  ·      Met5-enkephalin 🔍 Next Steps:  ·       Refining Secretion Host: Enhancing efficiency and expanding the range of producible proteins. ·      Enhanced Pre-Qualification: Developing a model to accurately predict protein secretability. ·      Future Directions: Scaling up to fed-batch to validate results under industrial conditions, evaluating continuous processing, and developing a comprehensive secretion data package. 📚 Upcoming Publications We will be publishing more detailed results from our studies in the coming weeks. We are committed to pushing the boundaries of protein production to drive scientific advancement and future therapeutic breakthroughs. Stay tuned for more updates!

Join Synonym, in collaboration with EV Biotech, Vectron Biosolutions, SynBioBeta and Enduro Genetics, for an insightful discussion on the critical role of strain engineering in the commercialization of bioproducts. Synonym and BCG’s recent report reveals that economies of scale alone are not sufficient for commercializing industrial bioproducts. Optimized strains designed for scale are pivotal for unlocking the massive potential of biomanufacturing in the coming decades. Our expert panel will explore the significance of strain optimization and its impact on increasing productivity, enhancing product quality, and achieving cost efficiency in biomanufacturing processes. 📅 Date: July 17, 2024 🕒 Time: 4pm to 5pm CET 📍 Register here: https://lnkd.in/ey4VDbzA Hear from an incredible lineup of industry leaders, and experts: Crystal Bleecher, PE VP (Science & Engineering) at @Synonym Christian Munch CEO at Enduro Genetics Linda Dijkshoorn CCO and Founder at EV Biotech Trond Erik Vee Aune CEO at Vectron Biosolutions AS Fiona Mischel (moderator), Director (International) at SynBioBeta Don't miss out on this opportunity to shape the future of sustainable development through biomanufacturing. To register, please visit this link. We look forward to seeing you there! #bioeconomy #biomanufacturing #sustainability #innovation #webinar #strainengineering #strainoptimization #fermentation #precisionfermentation

Caught up with Trond Erik Vee Aune, CEO Vectron Biosolutions AS during #bio2024 in #sandiego. Stop by if you are at the conference and learn about Vectron’s Microbial Protein Production Expertise. You can also find Vectron through our CDMO Advisor platform. https://lnkd.in/emWUdahe www.cdmoadvisor.com

Hola Barcelona! Starting Day 2 of #BioEuropeSpring Let‘s connect and discuss how Vectron Biosolutions AS can help you overcome the challenges at the early stages of development and increase your protein expression yield and purity, leading to faster and more affordable movement of your product towards the clinic or the market. #vectronbiosolutions #proteinexpression #straindevelopment #proteinproduction

Vectron Biosolutions Expands Services ✨ 
Elevating Microbial Protein Production for Scientific Advancements 🧬 We are proud to announce the expansion of our service offerings, aimed at optimizing every facet of microbial protein production for the scientific community. Our comprehensive suite of advanced services is tailored to address the evolving needs of researchers, providing impactful solutions across various stages of the production process. At the foundation of this pivotal expansion lies Vectron's profound expertise in the development of outstanding bacterial strains.   1️⃣ Enzyme Evolution and Screening:  Evaluate evolved enzyme activity and characterize new variants for improved enzymatic processes. 2️⃣ Strain Development and Screening: Establish and identify optimized recombinant protein-producing strains utilizing Vectron’s unique expression platform. 3️⃣ Fermentation: Seamlessly scale up to industrially relevant high cell density cultivation conditions, progressing from bench to pilot scale for efficient fermentation processes. 4️⃣ Upstream Process Characterization: Conduct in-depth analysis of metabolites, nutrients, online data, substrate/medium optimization, and by-product identification for a robust upstream process. 5️⃣ Purification/Protein Quality Assessment: Isolate the protein of interest at bench- and prep-scale, including evaluating endotoxin levels, host DNA, metals, etc., ensuring high-quality protein. 6️⃣ Protein Analysis: Rigorously assess product quality, covering intact mass, glycan and disulfide bond profiling. In-vitro characterization includes activity, binding affinity, anti-microbial, anti-fungal, and anti-viral activity, along with titer determination. Ready to optimize your microbial protein production journey? Let's explore the possibilities together! #VectronBiosolutions #StrainDevelopment #ProteinProduction #ProteinExpression #RecombinantProtein #Bioprocessing

Just a few days remain until #PEGSEurope in Lisbon! Introducing Karine Koppen, the newest research scientist at Vectron Biosolutions AS, who will be representing our company at the upcoming event, anticipated to be the largest PEGS Europe conference to date. Taking place from November 14th to 16th, the conference will serve as a focal point for the latest advancements in protein and antibody engineering, with a specific emphasis on new biological technologies.   Karine is really looking forward to taking part in her first-ever conference at Europe’s top biologics technology event. She is ready to absorb the latest insights and trends in biological technologies and pass on knowledge to her team. We are thrilled to have Karine as our representative and are eagerly anticipating her return, as she will undoubtedly bring back valuable insights that will further strengthen our position as innovators in the field. For more information about the conference, visit  https://lnkd.in/ge4ZTX5 #PEGS2023 #PEGSeurope #vectronbiosolutions #proteinengineering #drugdevelopment #straindevelopment

Vectron Biosolutions AS is excited to announce our new collaboration with Synonym! This collaboration will allow Vectron's customers to access Synonym's development and financing platform to accelerate their scale-up and commercialization efforts, while Synonym’s customers will be able to leverage Vectron's technology platform to improve their cost of production at scale. "In a CDMO industry primarily focused on delivering messages of manufacturing capacity, downstream processing technologies, and upstream processes resulting in impressive g/L titers, the key metric of dollars per gram of protein, is often hidden or overlooked,” added Trond Erik Vee Aune, CEO and Co-Founder of Vectron, continuing, “We are therefore excited to collaborate with Synonym and we are invested in their efforts to illuminate - and reduce - the actual costs of manufacturing at scale, especially for the growing Synbio industry." "We know how important strain performance is to the economic viability of industrial bioproducts,” said Joshua Lachter, Synonym's Co-Founder and Chief Business Officer. “We think Vectron offers a differentiated, industry-leading platform for optimizing strain performance and product quality, and we’re excited to offer their expertise to our partners." If you’re interested in improving your upstream process performance and scaling up your bioproduct, please get in touch with us at contact@vectronbiosolutions.com. #straindevelopment #biomanufacturing #bioeconomy #scaleup #vectronbiosolutions

Many incredible novel drug discoveries are being made without sustainable, widely adopted development solutions to support them, leaving a significant gap in the successful manufacturing of related therapeutic proteins. Cytovance Biologics' Senior Director of R&D, Stephanie Wickham, Ph.D, is leading the charge to find new solutions for our customers by expanding our access to cutting-edge technologies, including our recent partnership with Vectron Biosolutions AS. Read more at https://hubs.la/Q025kS2K0 #biomanufacturing #partnership #drugdevelopment