LifeCanvas Technologies Inc.

🏆 Congratulations to our three #LifeCanvasTravelGrant Winners for the Society for Neuroscience Conference 2024 in Chicago. Their groundbreaking research, utilizing our advanced imaging technologies, stood out among many impressive submissions. Winners and Their Research: Shreyas M Suryanarayana from the Josh Huang Lab at Duke University Neurobiology: 🧠 Evo-devo diversification of cortical output channels. 🔬 Featuring: Clear+ clearing pipeline and #SmartSPIM light sheet microscope. Albit Caban from the Ramirez Lab at Boston University: 🧠 Prefrontal cortex arbitrates memory-guided conflict resolution 🔬 Featuring: Clear+ clearing pipeline and, #SmartSPIM light sheet microscope. Sam Reynolds from the Meng Lab at University of New England: 🧠 Whole brain mapping of activity-dependent genetically labeled neurons after corneal stimulation 🔬 Featuring: #SmartBatch+ system for active tissue clearing and labeling, and, #SmartSPIM light sheet microscope. We are incredibly proud to support these innovative researchers by featuring their abstracts at our booth and social, and a big thank you to everyone who participated – the competition had many impressive abstracts. 📣 Stay tuned for more updates and exciting opportunities!

Happy #FluorescenceFriday!  Today, we’re thrilled to showcase our video showing c-FOS labeling (green) and detected c-FOS+ cells (red) in a mouse brain, imaged with #SmartSPIM at 3.6X magnification and analyzed with #SmartAnalytics. Why c-FOS? c-FOS is a protein derived from immediate early gene expression and is recognized as a specific marker of neuronal activity throughout the mammalian brain. Through a variety of perturbations (e.g. drug treatments, external stimuli), expression levels become elevated. By detecting c-FOS+ cells throughout tissue volumes via immunolabeling, imaging, and analyses, neural activity can be visualized, mapped, and quantified throughout the brain. Our end-to-end solutions for #3DSpatialBiology are designed to streamline your research and provide you with deep insights for a variety of applications, including neural function, from sample preparation to advance data analysis. Researching the complexities of brain activity? Connect with us today! https://lnkd.in/dNCwPWsA #neuroscience #research #brainmapping #lightsheetimaging #microscopy #brain

🔬 ✨ High-Resolution Imaging with #MegaSPIM! #MegaSPIM is setting new standards in light sheet microscopy by delivering unparalleled high-resolution volumetric imaging. Its capabilities extend across: - High-throughput imaging with exceptional detail. - Versatility for various tissue types, from thin sections and cleared thick sections to arrays of cleared whole rodent organs or organoids. - User-friendly software designed for seamless operation and streamlined post-processing. Just take a look at this remarkable image from Dr. Hongwei Dong's Lab at UCLA using #MegaSPIM for functional networking and connectome research. ➡ Want to see how #MegaSPIM can elevate your research? Learn more about MegaSPIM: https://lnkd.in/eXJKmD7m #lightsheet #3Dspatialbiology #imaging #neuroscience #research #brainresearch

Last week, we had the incredible opportunity to support the Tissue Clearing and Light Sheet Workshop at the University of Washington. This event, hosted by the #NAPE (Neuroscience of Addiction, Pain, and Emotion) consortium, brought together passionate researchers from over a dozen labs to explore the cutting-edge realm of light sheet imaging. We were thrilled to showcase our full pipeline for #3DSpatialBiology: from sample preparation, to light sheet imaging. - #SHIELD technology for excellent tissue preservation. - #SmartBatch+ for active tissue clearing and immunolabeling. - #SmartSPIM light sheet microscope providing the accuracy, speed and flexibility for generating the highest quality data. - #SmartAnalytics2 for detailed 3D analysis. A big thank you to the organizers: Jovanna Navarrete, Kentaro Ishii, Eric Szeleny, Jingyi Chen, Charles Zhou, Lusine Eyde, and Sam A. Golden university. Your efforts made this event a success!

We’re excited to share the recent study by Theodore Zwang from the Zwang Lab and Rachel Bennett from the Cambridge Bennet Alzheimer's Lab at Mass General Hospital and Harvard University. Their research leveraged our #MegaSPIM Light Sheet Microscope to show cerebral amyloid angiopathy pathology and tau accumulation near blood vessels in brains of individuals who have #Alzheimer’s disease. https://lnkd.in/dCqqNdqS

Check out the video from the new research published in Science Magazine. This work was led by our founder, Kwanghun Chung, with significant contributions from Jeffrey Stirman (CTO at LifeCanvas Technologies) and three former Chung Lab members at Massachusetts Institute of Technology who are now part of LifeCanvas Technologies: Ji Wang (Director of Mechanical Products), Nicholas Evans (Senior Microscope Engineer), and Webster Guan (Principal Image Data Scientist). The paper showcases how LifeCanvas' cutting-edge technologies, including #Megatome, #SHIELD, and #MegaSPIM, are transforming the study of human organs, particularly the brain. Read full article: https://lnkd.in/duhgpzE5 ✨ At LifeCanvas Technologies, our goal is to transform tissue imaging and analysis to empower researchers to conduct thorough, integrative analyses of human and animal tissues at unmatched speed and resolution.

Super proud of my coworkers at LifeCanvas. It’s no small feat to accomplish so much and to be published in such a prestigious journal. Looking forward to a bright future! ☀️🧠

🔬 Exciting News from LifeCanvas Technologies! We are excited to share the latest publication in Science, featuring groundbreaking research from the Chung Lab at Massachusetts Institute of Technology. This research, led by Kwanghun Chung, our founder, includes significant contributions from Jeffrey Stirman (CTO at LifeCanvas Technologies Inc.) and three former Chung Lab members who are now part of LifeCanvas Technologies Inc.: Ji Wang (Director of Mechanical Products), Nicholas Evans (Senior Microscope Engineer), and Webster Guan (Principal Image Data Scientist). 🧠 The paper showcases how LifeCanvas' cutting-edge technologies, including #MEGAtome, #SHIELD, and #MegaSPIM, are transforming the study of human organs, particularly the brain. - #SHIELD: Ensures permanent protein preservation through multiple imaging cycles. - #MEGAtome: Precision slicing for maintaining critical structural details in large biological samples. - #MegaSPIM: Captures multiscale data with high-throughput cellular resolution and adaptability for large tissue samples. These technologies have been pivotal in analyzing #Alzheimer's disease pathology in human brains, revealing detailed insights into cell distributions, neuronal structures, and synaptic connections. This holistic mapping approach opens new avenues for understanding complex brain disorders. ➡ At LifeCanvas Technologies, we’re committed to pushing the boundaries of tissue imaging and analysis. We believe this technology will significantly advance our knowledge of brain architecture and its alterations in diseases, paving the way for better diagnostics and therapies. Our goal is to empower researchers to conduct thorough, integrative analyses of human and animal brains at unmatched speed and resolution. 🔗 Full access here: https://lnkd.in/duhgpzE5

🔬🧠 Discover how #MegaSPIM is revolutionizing high-resolution light sheet microscopy! - High-throughput high-resolution volumetric imaging - Versatile tissue types, from thin sections, cleared thick sections, to arrays of cleared whole rodent organs or organoids - Simple, easy-to-use software with streamlined post-processing #MegaSPIM is transforming research across a wide range of applications. This image from Dr. Hongwei Dong Lab at UCLA highlights its use in functional networking and connectome research, offering unmatched detail and clarity. ➡ Curious about how #MegaSPIM can benefit your work? Speak to an imaging expert today: https://lnkd.in/eXJKmD7m #lightsheet #spatialbiology #innovation #microscopy #brain #research #neuroscience

🔬 #MicroscopyMonday Highlight: Exploring Psychedelics Through Whole-Brain Imaging! 🧠 Excited to share this publication leveraging whole-brain imaging of cellular c-Fos signals for #psychedelics drug discovery and see how this research can transform the future of neuroscience and therapeutics. Congratulations Alex Kwan Farid Aboharb, PhD, Pasha Davoudian! https://lnkd.in/dcJt7ZRc #neuroscience #brainresearch #microscopy #lightsheetimaging